Dr. McLaughlin discussed the scientific findings of his studies on Paw Paw compounds. He also summarizes the effects and method of action of the acetogenins.
There are over 100 scientific papers on the chemistry and biological effects of Paw Paw. It was also found that the Zebra Swallowtail butterfly eats the leaves of the Paw Paw plant. That butterfly is an obligate parasite of the plant. It constitutes a defense mechanism for the butterfly because birds that eat them become nauseous and vomit.
It was found in cancer research that Paw Paw works in four ways to affect cells.
- It slows or stops ATP production, which leads to a decrease in available cellular energy, which also results in programmed cell death (apoptosis). This causes a cessation of metastasis of cancer.
- Because ATP is necessary for DNA and RNA production, when it is not being produced, this leads to a reduction in cell reproduction. This effect also blocks viral replication, and may be an element responsible for Paw Paw’s beneficial effect on herpes, MS, hepatitis C, common cold, etc.
- Paw Paw causes a reduction in the levels of angiogenesis (the production of new blood vessels), which would have a tendency to reduce the growth rate of tumors. Tumors require a lot of blood vessels because of their great need for energy.
- Paw Paw shuts off the Multi Drug Resistant cell pumps that eliminate chemotherapy drugs from tumor cells. This can help restore the effectiveness of refractive chemotherapy drugs.
Remember that Paw Paw molecules are nontoxic. Researchers have found that it is impossible to overdose on Paw Paw because very high doses cause vomiting. In summary, acetogenins are more effective than common chemotherapeutic drugs, and they exhibit no toxicity. They also appear to be effective against viral infections such as herpes, multiple sclerosis, hepatitis, the common cold, etc.